Published
January 18, 2024

TARGET Trial

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TARGET Trial

This substudy aims to investigate the treatment effects of definitive treatment with intravenous cefazolin compared to (flu)cloxacillin in terms of 90-day mortality in Methicillin-resistant Staphylococcus aureus bacteraemia patients in the SNAP trial vs. those not in the SNAP trial.

Substudies in Progress

SNAP Trial

SABSI

Profiling the genetic and epigenetic determinants that predispose to severe manifestations of Staphylococcus aureus bacteremia

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All Interested
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Substudy in Progress

cfDNA

Cell-free DNA is a Versatile Analyte to Monitor Complications and Guide Treatment Duration in Staphylococcus aureus Bacteremia

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Any interested
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Substudy in Progress

SABSI-Outcomes

Derivation and Validation of Phenotypes of Staphylococcus aureus bloodstream infection, with Correlation with Outcome.

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Any Interested
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Substudy in Progress

SNAP-SEQ

Pilot study for real-time sequencing of Staphylococcus aureus bloodstream isolates

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Any Interested
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Substudy in Progress

PENFAST

Using a validated penicillin allergy risk prediction tool (Pen-FAST) in patients with a low risk penicillin allergy 

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Any Interested
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Substudy in Progress

Pharmacogenomics

 Immunopathogenesis and pharmacogenomics of severe antibiotic hypersensitivity 

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Australia
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Substudy in Progress
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